MICHNE, W. F.: search on Z-Library

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1

A practical synthesis of the enantiomers of hydroxychloroquine

Paul M. Blaney, Stephen J. Byard, Glynis Carr, George J. Ellames, John M. Herbert, James E. Peace, David I. Smith, William F. Michne, Mark S. Sanner

Journal:

Tetrahedron: Asymmetry

Year:

1994

Language:

english

File:

PDF, 544 KB

english, 1994

2

The 2006 Benjamin Franklin Medal in Chemistry presented to Samuel J. Danishefsky, Ph.D.

William F. Michne

Journal:

Journal of the Franklin Institute

Year:

2010

Language:

english

File:

PDF, 222 KB

english, 2010

3

ChemInform Abstract: SYNTHESIS AND NARCOTIC AGONIST-ANTAGONIST EVALUATION OF SOME 2,6-METHANO-3-BENZAZOCINE-11-PROPANOLS. ANALOGS OF THE RING C BRIDGED ORIPAVINE-7-METHANOLS

MICHNE, W. F., SALSBURY, R. L., MICHALEC, S. J.

Journal:

Chemischer Informationsdienst

Year:

1977

File:

PDF, 165 KB

1977

4

Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response

Quiniou, C., Dominguez-Punaro, M., Cloutier, F., Erfani, A., Ennaciri, J., Sivanesan, D., Sanchez, M., Chognard, G., Hou, X., Rivera, J. C., Beauchamp, C., Charron, G., Vilquin, M., Kuchroo, V., Michn

Journal:

AJP Regulatory Integrative and Comparative Physiology

Year:

2014

Language:

english

File:

PDF, 4.16 MB

english, 2014

5

Stereoselective Synthesis of New Conformationally Restricted Analogues of a Potent CGRP Receptor Antagonist

Zuev, Dmitry, Michne, Jodi A., Huang, Hong, Beno, Brett R., Wu, Dedong, Gao, Qi, Torrente, John R., Xu, Cen, Conway, Charles M., Macor, John E., Dubowchik, Gene M.

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 132 KB

english, 2005

6

Molecular modeling and mutagenesis of the ligand-binding pocket of the mGlu3 subtype of metabotropic glutamate receptor

Yi Yao, N. Pattabiraman, William F. Michne, Xi-Ping Huang, David R. Hampson

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 435 KB

english, 2003

7

Keto/Enol Epoxy Steroids as HIV-1 Tat Inhibitors: Structure-Activity Relationships and Pharmacophore Localization

Michne, William F., Schroeder, Joseph D., Bailey, Thomas R., Neumann, Helmut C., Cooke, Debra, Young, Dorothy C., Hughes, Joseph V., Kingsley, Susan D., Ryan, Kathryn A., Putz, Henry S., Shaw, Lucinda

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.32 MB

english, 1995

8

An Efficient Sequence for the Preparation of Small Secondary Amine Hydrochloride Salts for Focused Library Generation Without Need for Distillation or Chromatographic Purification.

Gene M. Dubowchik, Jodi A. Michne, Dmitry Zuev

Journal:

Year:

2004

File:

PDF, 26 KB

2004

9

Pharmacological profiles of tonazocine (Win 42156) and zenazocine (Win 42964)

Susan J Ward, Anne K Pierson, William F Michne

Journal:

Year:

1985

Language:

english

File:

PDF, 279 KB

english, 1985

10

2-Arylaminothiazoles as high-affinity corticotropin-Releasing factor 1 receptor (CRF1R) antagonists: synthesis, binding studies and behavioral efficacy

Gene M. Dubowchik, Jodi A. Michne, Dmitry Zuev, Wendy Schwartz, Paul M. Scola, Clint A. James, Edward H. Ruediger, Sokhom S. Pin, Kevin D. Burris, Lynn A. Balanda, Qi Gao, Dedong Wu, Lawrence Fung, Tr

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 214 KB

english, 2003

11

ChemInform Abstract: BENZOMORPHANS. STRUCTURE OF A POSITION ISOMER

ALBERTSON, N. F., MICHNE, W. F., TULLAR, B. F.

Journal:

Chemischer Informationsdienst

Year:

1978

File:

PDF, 125 KB

1978

12

Benzo[g]quinolines. II. Novel synthesis and pharmacological evaluation of cis-1-alkyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolines

Michne, William F., Albertson, Noel F.

Journal:

Journal of Medicinal Chemistry

Year:

1970

Language:

english

File:

PDF, 464 KB

english, 1970

13

ChemInform Abstract: A 2,6-METHANO-3-BENZAZOCINE RELATED TO THE THEBAINE DIELS-ALDER ADDUCT DERIVATIVES

Journal:

Chemischer Informationsdienst

Year:

1976

File:

PDF, 220 KB

1976

14

Benzo[g]quinolines. I. Synthesis and pharmacological evaluation of cis- and trans-1-alkyl-5,5-dimethyl-1,2,3,4a,5,10,10a-octahydrobenzo[g]quinolin-7-ol. A class of narcotic antagonists

Michne, William F., Albertson, N. F.

Journal:

Journal of Medicinal Chemistry

Year:

1969

Language:

english

File:

PDF, 489 KB

english, 1969

15

Effect of Win 44441-3 and naloxone on endotoxin-induced hypotensive shock in anesthetized hypertensive rats

A.F. DeFelice, J.D. Norton, H.E. Lape, W.F. Michne

Journal:

Year:

1985

Language:

english

File:

PDF, 294 KB

english, 1985

16

Benzo[g]quinolines. 3. Influence of carbon-5 substituents on narcotic antagonist and antiwrithing activities of derivatives of cis-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-7-ol

Michne, William F.

Journal:

Journal of Medicinal Chemistry

Year:

1976

Language:

english

File:

PDF, 367 KB

english, 1976

17

ChemInform Abstract: 2,6-METHANO-3-BENZAZOCINE-11-PROPANOLS. LACK OF ANTAGONISM BETWEEN OPTICAL ANTIPODES AND OBSERVATION OF POTENT NARCOTIC ANTAGONISM BY TWO N-METHYL DERIVATIVES

Journal:

Chemischer Informationsdienst

Year:

1979

File:

PDF, 216 KB

1979

18

Analgesic 1-oxidized-2,6-methano-3-benzazocines

Michne, William F., Albertson, Noel F.

Journal:

Journal of Medicinal Chemistry

Year:

1972

Language:

english

File:

PDF, 500 KB

english, 1972

19

Novel Inhibitors of the Nuclear Factor of Activated T Cells (NFAT)-Mediated Transcription of .beta.-Galactosidase: Potential Immunosuppressive and Antiinflammatory Agents

Michne, William F., Schroeder, Joseph D., Guiles, Joseph W., Treasurywala, Adi M., Weigelt, Carolyn A., Stansberry, Mary F., McAvoy, Elizabeth, Shah, Chandra R., Bump, Elizabeth

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 2.53 MB

english, 1995

20

New analogs of cyclo(Prn-Prn): synthesis of unsymmetric octahydro-1H,5H-dipyrrolo[1,2-a:1'2'-d]pyrazine-5,10-diones

Sanner, Mark A., Weigelt, Carolyn, Stansberry, Mary, Killeen, Kelly, Michne, William F., Kessler, Donald W., Kullnig, Rudolph K.

Journal:

Journal of Organic Chemistry

Year:

1992

Language:

english

File:

PDF, 727 KB

english, 1992

21

Keto/enol epoxy steroids: a new structural class of HIV-1 tat inhibitors

Michne, William F., Schroeder, Joseph D., Bailey, Thomas R., Young, Dorothy C., Hughes, Joseph V., Dutko, Frank J.

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 266 KB

english, 1993

22

Electronic Spectroscopy and Photodissociation Dynamics of Hydrated Co 2+ Clusters: Co 2+ (H 2 O) n ( n = 4−7)

Faherty, Kieron P., Thompson, Christopher J., Aguirre, Fernando, Michne, Jodi, Metz, Ricardo B.

Journal:

Journal of Physical Chemistry A

Year:

2001

Language:

english

File:

PDF, 81 KB

english, 2001

23

Editorial [Hot Topic: Chemical Effectors in Drug Discovery (Guest Editor: William F. Michne)]

Michne, William

Journal:

Current Topics in Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 22 KB

english, 2005

24

ChemInform Abstract: BENZO(G)CHINOLINE 2. MITT. SYNTH. UND PHARMAKOLOGISCHE AUSWERTUNG VON CIS-1-ALKYL-1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO(G)CHINOLINEN

MICHNE, W. F., ALBERTSON, N. F.

Journal:

Chemischer Informationsdienst. Organische Chemie

Year:

1970

File:

PDF, 244 KB

1970

25

Quinone methide from 4-hydroxybenzyl alcohol diacetate: (P-acetoxy)benzylation of β-dicarbonyls

Mark A. Sanner, Mary Stansberry, Carolyn Weigelt, William F. Michne

Journal:

Tetrahedron Letters

Year:

1992

Language:

english

File:

PDF, 156 KB

english, 1992

26

(2,6-Methano-3-benzazocin-11.beta.-yl)alkanones. 1. Alkylalkanones: a new series of N-methyl derivatives with novel opiate activity profiles

Michne, William F., Lewis, Thomas R., Michalec, Stephen J., Pierson, Anne K., Rosenberg, Franklin J.

Journal:

Journal of Medicinal Chemistry

Year:

1979

Language:

english

File:

PDF, 711 KB

english, 1979

27

ChemInform Abstract: (2,6-METHANO-3-BENZAZOCIN-11β-YL)ALKANONES. 1. ALKYLALKANONES: A NEW SERIES OF N-METHYL DERIVATIVES WITH NOVEL OPIATE ACTIVITY PROFILES

MICHNE, W. F., LEWIS, T. R., MICHALEC, S. J., PIERSON, A. K., ROSENBERG, F. J.

Journal:

Chemischer Informationsdienst

Year:

1980

File:

PDF, 222 KB

1980

28

An efficient sequence for the preparation of small secondary amine hydrochloride salts for focused library generation without need for distillation or chromatographic purification

Gene M. Dubowchik, Jodi A. Michne, Dmitry Zuev

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 242 KB

english, 2004

29

ChemInform Abstract: BENZO(G)QUINOLINES. 3. INFLUENCE OF CARBON-5 SUBSTITUENTS ON NARCOTIC ANTAGONIST AND ANTIWRITHING ACTIVITIES OF DERIVATIVES OF CIS-1,2,3,4,4A,5,10,10A-OCTAHYDROBENZO(G)QUINOLIN-7-OL

Journal:

Chemischer Informationsdienst

Year:

1977

File:

PDF, 130 KB

1977

30

Optimization of CRF1R binding affinity of 2-(2,4,6-trichlorophenyl)-4-trifluoromethyl-5-aminomethylthiazoles through rapid and selective parallel synthesis

Dmitry Zuev, Jodi A. Michne, Sokhom S. Pin, Jie Zhang, Matthew T. Taber, Gene M. Dubowchik

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 258 KB

english, 2005

31

2,6-Methano-3-benzazocine-11-propanols. Lack of antagonism between optical antipodes and observation of potent narcotic antagonism by two N-methyl derivatives

Michne, William F.

Journal:

Journal of Medicinal Chemistry

Year:

1978

Language:

english

File:

PDF, 373 KB

english, 1978

32

Synthesis and narcotic agonist-antagonist evaluation of some 2,6-methano-3-benzazocine-11-propanols. Analogs of the ring C bridged oripavine-7-methanols

Michne, William F., Salsbury, Ronald L., Michalec, Stephen J.

Journal:

Journal of Medicinal Chemistry

Year:

1977

Language:

english

File:

PDF, 689 KB

english, 1977

33

Discovery of 6-chloro-2-trifluoromethyl-7-aryl-7H-imidazo[1,2-a]imidazol-3-ylmethylamines, a novel class of corticotropin-releasing factor receptor type 1 (CRF1R) antagonists

Dmitry Zuev, Vivekananda M. Vrudhula, Jodi A. Michne, Bireshwar Dasgupta, Sokhom S. Pin, Xiaohua Stella Huang, Dedong Wu, Qi Gao, Jie Zhang, Matthew T. Taber, John E. Macor, Gene M. Dubowchik

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 702 KB

english, 2010

34

Novel Inhibitors of Potassium Ion Channels on Human T Lymphocytes

Michne, William F., Guiles, Joseph W., Treasurywala, Adi M., Castonguay, Laurie A., Weigelt, Carolyn A., Oconnor, Bernard, Volberg, Walter A., Grant, Alison M., Chadwick, Christopher C., Krafte, Dougl

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 1.88 MB

english, 1995

35

Design and synthesis of a β-strand inducer Application to ICAM-1/LFA-1 mediated cellular adhesion

WILLIAM F. MICHNE, JOSEPH D. SCHROEDER

Journal:

Chemical Biology & Drug Design

Year:

1996

Language:

english

File:

PDF, 699 KB

english, 1996

36

Benzomorphans. Structure of a position isomer

Albertson, N. F., Michne, W. F., Tullar, B. F.

Journal:

Journal of Medicinal Chemistry

Year:

1978

Language:

english

File:

PDF, 507 KB

english, 1978

37

ChemInform Abstract: ANALGETISCH WIRKSAME, 1-OXIDIERTE 2,6-METHANO-3-BENZAZOCINE

MICHNE, W. F., ALBERTSON, N. F.

Journal:

Chemischer Informationsdienst

Year:

1973

File:

PDF, 222 KB

1973

38

ChemInform Abstract: SYNTHESIS AND NARCOTIC AGONIST-ANTAGONIST EVALUATION OF SOME 2,6-METHANO-3-BENZAZOCINE-11-PROPANOLS. ANALOGS OF THE RING C BRIDGED ORIPAVINE-7-METHANOLS

MICHNE, W. F., SALSBURY, R. L., MICHALEC, S. J.

Journal:

Chemischer Informationsdienst

Year:

1977

File:

PDF, 165 KB

1977

39

Synthesis, structure–activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists

Xiaojun Han, Jodi A. Michne, Sokhom S. Pin, Kevin D. Burris, Lynn A. Balanda, Lawrence K. Fung, Tracey Fiedler, Kaitlin E. Browman, Matthew T. Taber, Jie Zhang, Gene M. Dubowchik

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 230 KB

english, 2005

40

A 2,6-methano-3-benzazocine related to the thebaine Diels-Alder adduct derivatives

Michne, William F.

Journal:

Journal of Organic Chemistry

Year:

1976

Language:

english

File:

PDF, 377 KB

english, 1976

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